Abstract Background Activated T cells play a pivotal role in rheumatoid arthritis (RA) pathogenesis. and imaging of activated T cells may provide a non-invasive tool for RA detection. Here. we first developed an optical probe targeting human inducible T cell co-stimulator (ICOS) and tested its capacity in RA diagnosis by capturing ICOS+ activated T cells in vivo in a humanized mouse m... https://fitnessgravesyardes.shop/product-category/crank-shaft/